Article
Odorant receptor gene regulation: implications from genomic organization.
Trends in genetics : TIG - 1 Jan 2002
Kratz Erica, Dugas Jason C, Ngai John
Abstract excerpt
Odorant receptor genes comprise the largest known family of G-protein-coupled receptors in vertebrates. These receptor genes are tightly clustered in the genomes of every vertebrate organism investigated, including zebrafish, mice and humans, and they appear to have expanded and duplicated throughout evolution. In a mechanism that has yet to be elucidated, each olfactory neuron expresses a single receptor gene....
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