Article
The promoter of the mouse odorant receptor gene M71.
Molecular and cellular neurosciences - 1 Mar 2005
Rothman Andrea, Feinstein Paul, Hirota Junji, Mombaerts Peter
Abstract excerpt
From a repertoire of approximately 2000 odorant receptor (OR) alleles in the mouse genome, a mature olfactory sensory neuron (OSN) is thought to choose only one functional allele of one OR gene for expression. OSNs that express a given OR gene are scattered throughout an epithelial region that is gene specific. The DNA sequences that enable OR gene choice and specify the epithelial pattern are not known. Within...
Topics
- Animals
- Base Sequence
- Binding Sites
- Female
- Gene Expression Regulation
- Gene Targeting
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Mice, Transgenic
- Molecular Sequence Data
- Multigene Family
- Mutation
- Olfactory Mucosa
- Olfactory Receptor Neurons
- Promoter Regions, Genetic
- Receptors, Odorant
