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Article

Myelomonocytic skewing in chronic myelomonocytic leukemia: phenotypic, molecular and biologic features and impact on survival.

European journal of haematology - 1 May 2021

Geissler Klaus, Jäger Eva, Barna Agnes, Graf Temeida, Graf Elmir, Öhler Leopold, Hoermann Gregor, Valent Peter

Abstract excerpt

BACKGROUND: Myelomonocytic skewing is considered as a key pathophysiologic phenomenon in chronic myelomonocytic leukemia (CMML), but its prevalence and potential correlation with phenotypic, genotypic, and clinical features are poorly defined. METHODS: Skewed differentiation toward the myelomonocytic over erythroid commitment as indicated by an inverse ratio of myelomonocytic/erythroid colonies was investigated...

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Identifiers

PMID: 33432601
DOI: 10.1111/ejh.13577
PMCID: PMC8554855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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