Oligomonocytic chronic myelomonocytic leukemia (chronic myelomonocytic leukemia without absolute monocytosis) displays a similar clinicopathologic and mutational profile to classical chronic myelomonocytic leukemia.

doi:10.1038/modpathol.2017.45

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Article

Oligomonocytic chronic myelomonocytic leukemia (chronic myelomonocytic leukemia without absolute monocytosis) displays a similar clinicopathologic and mutational profile to classical chronic myelomonocytic leukemia.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2017

Geyer Julia T, Tam Wayne, Liu Yen-Chun, Chen Zhengming, Wang Sa A, Bueso-Ramos Carlos, Oak Jean, Arber Daniel A, Hsi Eric, Rogers Heesun J, Levinson Katherine, Bagg Adam, Hassane Duane C, Hasserjian Robert P, Orazi Attilio

Abstract excerpt

Chronic myelomonocytic leukemia is characterized by persistent absolute monocytosis (≥1 × 109/l) in the peripheral blood and dysplasia in ≥1 lineages. In the absence of dysplasia, an acquired clonal genetic abnormality is required or causes for reactive monocytosis have to be excluded. Oligomonocytic chronic myelomonocytic leukemia showing increased monocytes but no absolute monocytosis in the peripheral blood...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28548124
DOI: 10.1038/modpathol.2017.45

Genes

ASXL1
CBL
SRSF2
TET2

Provenance

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