Article
Chronic myelomonocytic leukemia evolving from preexisting myelodysplasia shares many features with de novo disease.
American journal of clinical pathology - 1 Nov 2006
Wang Sa A, Galili Naomi, Cerny Jan, Sechman Eric, Chen Su Sin, Loew Jerome, Liu Qin, Fadare Oluwole, Hasserjian Robert, Jones Dan, Qawi Huma, Woda Bruce, Raza Azra
Abstract excerpt
The majority of chronic myelomonocytic leukemia (CMML) cases arise de novo; cases evolving from preexisting myelodysplasia (MDS) or myeloproliferative diseases have not been well-studied. We conducted the present study to determine the clinicopathologic features and to study possible underlying molecular and cytogenetic mechanisms involved in this evolution. Between April 1995 and November 2005, we identified 120...
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