Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation Between Immunohistochemistry and Sequencing in H3G34-Mutant Gliomas.

The American journal of surgical pathology - 1 Feb 2021

Gianno Francesca, Antonelli Manila, Di Dio Tiziano, Minasi Simone, Donofrio Vittoria, Buccoliero Anna M, Gardiman Marina P, Pollo Bianca, Diomedi Camassei Francesca, Rossi Sabrina, Novello Mariangela, Giangaspero Felice, Arcella Antonietta, Gessi Marco, Buttarelli Francesca R

Abstract excerpt

Recurrent glycine-to-arginine/valine alterations at codon 34 (G34R/V) within H3F3A gene characterize a subset of hemispheric high-grade gliomas (HGG) affecting children and young adults. These tumors, defined as G34R/V-mutant gliomas, are histologically heterogenous, with microscopic features of either HGG or embryonal tumors (primitve neuroectodermal tumor-like features). To assess the value of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Glioma

Share to Histones

Share to Immunohistochemistry

Share to Infant

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 33428336
DOI: 10.1097/PAS.0000000000001571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation Between Immunohistochemistry and Sequencing in H3G34-Mutant Gliomas.PMID 33428336Read ↗

Low-Grade Gemistocytic Morphology in H3 G34R-Mutant Gliomas and Concurrent K27M Mutation: Clinicopathologic Findings.Semantic proximity Read ↗

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity.Semantic proximity Read ↗

Cerebral hemispheric glioblastoma with PNET-like morphology and histone H3.3 G34 mutation in younger patients: Report of three rare cases and diagnostic pitfalls.Semantic proximity Read ↗

Radiological and Immunostaining Characteristics of H3.3 G34R-Mutant Glioma: A Report of 3 Cases and Review of the Literature.Semantic proximity Read ↗

H3 G34-mutant high-grade glioma.Semantic proximity Read ↗

H3.3 G34R mutations in pediatric primitive neuroectodermal tumors of central nervous system (CNS-PNET) and pediatric glioblastomas: possible diagnostic and therapeutic implications?Semantic proximity Read ↗

The prognostic significance of further genotyping H3G34 diffuse hemispheric gliomas.Semantic proximity Read ↗

Evaluating H3F3A K27M and G34R/V somatic mutations in a cohort of pediatric brain tumors of different and rare histologies.Semantic proximity Read ↗

Diffuse hemispheric glioma, H3 G34-mutant: Genomic landscape of a new tumor entity and prospects for targeted therapySemantic proximity Read ↗

Historadiological correlations in high-grade glioma with the histone 3.3 G34R mutation.Semantic proximity Read ↗

Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.Semantic proximity Read ↗

Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.