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Article

Targeting STAT3 by a small molecule suppresses pancreatic cancer progression

8 Jan 2021

Abstract excerpt

Pancreatic cancer is lethal in over 90% of cases since it is resistant to current therapeutic strategies. The key role of STAT3 in promoting pancreatic cancer progression has been proven, but effective interventions that suppress STAT3 activities are limited. The development of novel anticancer agents that directly target STAT3 may have potential clinical benefits for pancreatic cancer treatment. Here, we report...

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PMID: 33420372
DOI: 10.1038/s41388-020-01626-z

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