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Article

Negative regulators of STAT3 signaling pathway in cancers

1 May 2019

Abstract excerpt

STAT3 is the most ubiquitous member of the STAT family and involved in many biological processes, such as cell proliferation, differentiation, and apoptosis. Mounting evidence has revealed that STAT3 is aberrantly activated in many malignant tumors and plays a critical role in cancer progression. STAT3 is usually regarded as an effective molecular target for cancer treatment, and abolishing the STAT3 activity may...

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PMID: 31213912
DOI: 10.2147/cmar.s206175

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