Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro.

Viruses - 6 Jan 2021

Hashizume Mei, Gonzalez Gabriel, Ono Chikako, Takashima Ayako, Iwasaki Masaharu

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), employs host-cell angiotensin-converting enzyme 2 (ACE2) for cell entry. Genetic analyses of ACE2 have identified several single-nucleotide polymorphisms (SNPs) specific to different human populations. Molecular dynamics simulations have indicated that several of these SNPs could affect...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Dynamics Simulation

Share to Mutagenesis

Share to Neutralization Tests

Share to Receptors, Virus

Share to SARS-CoV-2

Share to Virus Internalization

Source

Open in PubMed Open full text

Identifiers

PMID: 33418950
DOI: 10.3390/v13010067
PMCID: PMC7825141

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro.PMID 33418950Read ↗

Human ACE2 receptor polymorphisms predict SARS-CoV-2 susceptibilitySemantic proximity Read ↗

Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2.Semantic proximity Read ↗

Susceptibilities of human ACE2 genetic variants in coronavirus infectionSemantic proximity Read ↗

Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.Semantic proximity Read ↗

ACE2 polymorphisms and individual susceptibility to SARS-CoV-2 infection: insights from an <i>in silico</i> studySemantic proximity Read ↗

Comparative analysis of ACE2 mutations and their impact on SARS-CoV-2 susceptibility within diverse ethnic groups.Semantic proximity Read ↗

Missense variants in ACE2 are predicted to encourage and inhibit interaction with SARS-CoV-2 Spike and contribute to genetic risk in COVID-19Semantic proximity Read ↗

Genetic variability of human angiotensin‐converting enzyme 2 (hACE2) among various ethnic populationsSemantic proximity Read ↗

Genetic variations in the human severe acute respiratory syndrome coronavirus receptor ACE2 and serine protease TMPRSS2.Semantic proximity Read ↗

Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infectionSemantic proximity Read ↗

Mutations in spike protein and allele variations in ACE2 impact targeted therapy strategies against SARS-CoV-2.Semantic proximity Read ↗

ACE2 polymorphism and susceptibility for SARS-CoV-2 infection and severity of COVID-19.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.