Article
Susceptibilities of Human ACE2 Genetic Variants in Coronavirus Infection.
Journal of virology - 12 Jan 2022
Ren Wenlin, Zhu Yunkai, Lan Jun, Chen Hedi, Wang Yuyan, Shi Hongyang, Feng Fei, Chen Da-Yuan, Close Brianna, Zhao Xiaomin, Wu Jianping, Tian Boxue, Yuan Zhenghong, Zhou Dongming, Saeed Mohsan, Wang Xinquan, Zhang Rong, Ding Qiang
Abstract excerpt
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 235 million cases worldwide and 4.8 million deaths (October 2021), with various incidences and mortalities among regions/ethnicities. The coronaviruses SARS-CoV, SARS-CoV-2, and HCoV-NL63 utilize the angiotensin-converting enzyme 2 (ACE2) as the receptor to enter...
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