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Article

TT polymorphism in rs2165241 and rs1048661 region in lysyl oxidase like-1 gene may have a role in stress urinary incontinence physiopathology.

The journal of obstetrics and gynaecology research - 1 Jan 2013

Ozbek Emin, Polat Emre Can, Ozcan Levent, Otunctemur Alper, Emrence Zeliha, Ustek Duran

Abstract excerpt

AIM: In experimental studies, lysyl oxidase like-1 (LOX-L1) (-/-) mice were shown to have similar pelvic floor dysfunction to female rats. LOX-L1 levels in endopelvic fascia decrease as a result of increasing births in women with pelvic prolapse. For these reasons, we investigated the LOX-L1 gene polymorphism, which has an important role in connective tissue and collagenous metabolism in stress urinary...

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Source

Identifiers

PMID: 22765198
DOI: 10.1111/j.1447-0756.2012.01942.x

Genes

LOX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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