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Cell-specific characterization of the placental methylome

6 Jan 2021

Abstract excerpt

BACKGROUND: DNA methylation (DNAm) profiling has emerged as a powerful tool for characterizing the placental methylome. However, previous studies have focused primarily on whole placental tissue, which is a mixture of epigenetically distinct cell populations. Here, we present the first methylome-wide analysis of first trimester (n = 9) and term (n = 19) human placental samples of four cell populations:...

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PMID: 33407091
DOI: 10.1186/s12864-020-07186-6

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