Article
A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks.
Nucleic acids research - 25 Jan 2021
Hatkevich Talia, Miller Danny E, Turcotte Carolyn A, Miller Margaret C, Sekelsky Jeff
Abstract excerpt
Programmed DNA double-strand breaks (DSBs) made during meiosis are repaired by recombination with the homologous chromosome to generate, at selected sites, reciprocal crossovers that are critical for the proper separation of homologs in the first meiotic division. Backup repair processes can compensate when the normal meiotic recombination processes are non-functional. We describe a novel backup repair mechanism...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
