Article
A rare RET mutation in an Indian pedigree with familial medullary thyroid carcinoma.
Indian journal of cancer - 1 Jan 2000
Vijayan Roopa, Nair Vasantha, Menon Usha, Kumar Harish
Abstract excerpt
Familial medullary thyroid carcinoma (FMTC) is a variant of multiple endocrine neoplasia type 2 (MEN2) associated with the RET gene mutation. We report a rare RET mutation of c.2671T>G; p.Ser891Ala in Exon 15 of the RET gene in an Indian pedigree where seven family members out of 14 screened were found to be positive for the same. RET genetic analysis should be considered as an early approach in the diagnosis of...
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