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Article

Screening of RET gene mutations in Chinese patients with medullary thyroid carcinoma and their relatives.

Familial cancer - 1 Jan 2016

Wang Junyi, Zhang Bin, Liu Wensheng, Zhang Yongxia, Di Xuebing, Yang Yanmei, Yan Dangui

Abstract excerpt

The rearranged during transfection (RET) gene is a proto-oncogene; active mutations frequently occur in medullary thyroid carcinoma (MTC). This study investigated the spectrum of germline RET mutations and clinical features in Chinese hereditary MTC patients. A total of 53 family members from 11 different hereditary MTC families were recruited for detection of RET exon 8, 10, 11, 13, 14, 15, and 16 mutations, in...

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Source

Identifiers

PMID: 26254625
DOI: 10.1007/s10689-015-9828-6

Genes

RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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