Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rare RET Variant p.D707E in a Chinese Pedigree with Hereditary Medullary Thyroid Carcinoma.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2017

Zhang Lu, Li Xiaoyu, Li Qiyuan, Ge Shengxiang, Chen Mengyuan, Huang Shuizhen, Chen Binbin, Li Peng, Teng Bogang, Xu Jing, Zhao Shupeng, Qi Fengjie, Zhang Yongxing

Abstract excerpt

BACKGROUND: Hereditary medullary thyroid carcinoma (HMTC) is thought to be associated with germline mutations of the RET proto-oncogene. METHODS: We detected RET proto-oncogene germline mutations from a pedigree with HMTC in the east of China and investigated the characteristics of these mutations in this pedigree and their correlation with HMTC by direct sequencing of all 21 exons in the RET gene of all 46...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Carcinoma, Medullary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Multiple Endocrine Neoplasia Type 2a

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins c-ret

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 27798940
DOI: 10.1159/000448845

Genes

RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rare RET Variant p.D707E in a Chinese Pedigree with Hereditary Medullary Thyroid Carcinoma.PMID 27798940Read ↗

Case report: a p.C618S RET proto-oncogene germline mutation in a large Chinese pedigree with familial medullary thyroid carcinoma.Semantic proximity Read ↗

Chinese siblings with hereditary medullary thyroid carcinoma caused by RET mutation: implications for RET oncogene detection.Semantic proximity Read ↗

A rare RET mutation in an Indian pedigree with familial medullary thyroid carcinoma.Semantic proximity Read ↗

RET Proto-Oncogene Mutational Analysis in Patients With Medullary Thyroid CarcinomaSemantic proximity Read ↗

Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid CarcinomaSemantic proximity Read ↗

Twenty-Five Years Experience on RET Genetic Screening on Hereditary MTC: An Update on The Prevalence of Germline RET MutationsSemantic proximity Read ↗

A Korean family of familial medullary thyroid cancer with Cys618Ser RET germline mutation.Semantic proximity Read ↗

Screening of RET gene mutations in Chinese patients with medullary thyroid carcinoma and their relatives.Semantic proximity Read ↗

Molecular Analysis of the RET Proto-Oncogene Key Exons in Patients with Medullary Thyroid Carcinoma: A Comprehensive Study of the Iranian PopulationSemantic proximity Read ↗

Medullary thyroid carcinoma (MTC) and RET proto-oncogene: mutation spectrum in the familial cases and a meta-analysis of studies on the sporadic form.Semantic proximity Read ↗

Diversity of mutations in the RET proto-oncogene and its oncogenic mechanism in medullary thyroid cancer.Semantic proximity Read ↗

Novel RET Proto-oncogene variants identified in Turkish patients with thyroid carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.