Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of xenobiotic-metabolizing gene polymorphisms on breast cancer risk in South Indian women.

Breast cancer research and treatment - 1 Apr 2021

Rajagopal Taruna, Seshachalam Arun, Rathnam Krishna Kumar, Jothi Arunachalam, Talluri Srikanth, Venkatabalasubramanian Sivaramakrishnan, Dunna Nageswara Rao

Abstract excerpt

BACKGROUND: Functional variants of the xenobiotic-metabolizing genes (XMG) might modulate breast cancer (BC) risk by altering the rate of metabolism and clearance of myriad types of potent carcinogens from the breast tissue. Despite mounting evidence on the role of XMG variants on BC risk, the current knowledge regarding their influence on BC development is still fragmentary. METHODS: The present study examined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Glutathione Transferase

Share to Polymorphism, Genetic

Share to Risk Factors

Share to Xenobiotics

Source

Identifiers

PMID: 33392841
DOI: 10.1007/s10549-020-06028-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of xenobiotic-metabolizing gene polymorphisms on breast cancer risk in South Indian women.PMID 33392841Read ↗

Role of xenobiotic metabolizing gene polymorphisms in breast cancer susceptibility and treatment outcome.Semantic proximity Read ↗

Investigating the Role of Glutathione S- Transferase Genes, Histopathological and Molecular Subtypes, Gene-Gene Interaction and Its Susceptibility to Breast Carcinoma in Ethnic North- Indian Population.Semantic proximity Read ↗

Polymorphisms in GSTT1 and GSTM1 genes as possible risk factors for susceptibility to breast cancer development and their influence in chemotherapy response: a systematic review.Semantic proximity Read ↗

Meta-analysis of genetic polymorphisms in xenobiotic metabolizing enzymes and their association with breast cancer risk.Semantic proximity Read ↗

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?Semantic proximity Read ↗

Genetic susceptibility to breast cancer in French-Canadians: role of carcinogen-metabolizing enzymes and gene-environment interactions.Semantic proximity Read ↗

CYP1A1 and GSTP1 gene variations in breast cancer: a systematic review and case-control study.Semantic proximity Read ↗

Detection and relevance of germline genetic polymorphisms in glutathione S-transferases (GSTs) in breast cancer patients from northern Indian population.Semantic proximity Read ↗

Evaluation of breast cancer risk in a multigenic model including low penetrance genes involved in xenobiotic and estrogen metabolisms.Semantic proximity Read ↗

Polymorphisms in drug-metabolizing genes and urinary bladder cancer susceptibility and prognosis: Possible impacts and future management.Semantic proximity Read ↗

Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.Semantic proximity Read ↗

Combined effect of smoking and polymorphisms in tobacco carcinogen-metabolizing enzymes CYP1A1 and GSTM1 on the head and neck cancer risk in North Indians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.