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Article

Role of xenobiotic metabolizing gene polymorphisms in breast cancer susceptibility and treatment outcome.

Mutation research - 7 Mar 2005

Chacko Priya, Joseph Thomas, Mathew Beela Sarah, Rajan Balakrishnan, Pillai M Radhakrishna

Abstract excerpt

Metabolic activation and inactivation of potential genotoxic agents occur by Phase I and Phase II enzymes in multiple interactions. An expanding body of literature demonstrates that ethnic differences in breast cancer incidence may be partly caused by host genetic factors particularly genetic pol...

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Source

Identifiers

PMID: 15725614
DOI: 10.1016/j.mrgentox.2004.11.018

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15725614-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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