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Article

Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.

BMC medical genetics - 5 Jul 2008

Siraj Abdul K, Ibrahim Muna, Al-Rasheed Maha, Abubaker Jehad, Bu Rong, Siddiqui Shakaib U, Al-Dayel Fouad, Al-Sanea Osama, Al-Nuaim Abdulrahman, Uddin Shahab, Al-Kuraya Khawla

Abstract excerpt

BACKGROUND: The xenobiotic enzyme system that enables us to detoxify carcinogens exhibits identifiable genetic polymorphisms that are highly race specific. We hypothesized that polymorphisms of these genes may be associated with risk of thyroid cancer. To evaluate the role of genetic polymorphisms of xenobiotic genes in thyroid cancer, we conducted a hospital-based case-control study in Saudi population. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP1A1

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Source

Open in PubMed Open full text

Identifiers

PMID: 18601742
DOI: 10.1186/1471-2350-9-61
PMCID: PMC2492854

Genes

GSTM1
GSTT1
GSTP1
MTHFR
NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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