Article
Meta-analysis of association between the +49A/G polymorphism of cytotoxic T-lymphocyte antigen-4 and thyroid associated ophthalmopathy.
Current eye research - 1 Jan 2015
Wang Hao, Zhu Li-Shuang, Cheng Jin-Wei, Cai Ji-Ping, Li You, Ma Xiao-Ye, Wei Rui-Li
Abstract excerpt
PURPOSE OF THE STUDY: Cytotoxic-T lymphocyte antigen-4 (CTLA-4) has been shown to play an important role in the development and progression of thyroid associated ophthalmopathy (TAO). A number of case-control studies focused on the association between CTLA-4 +49A/G polymorphism and risk for TAO. But the results were not always consistent. So we performed a meta-analysis to evaluate the precise association between...
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