Article
Programmed cell death 1 (PDCD1) gene haplotypes and susceptibility of patients to basal cell carcinoma.
Molecular biology reports - 1 Mar 2021
Fathi Farshid, Zamani Batool, Piroozmand Ahmad, Mozafarpoor Samaneh, Seyedhashemi Effat, ArefNezhad Reza, Motedayyen Hossein
Abstract excerpt
Programmed death-1 (PD-1), as an immunoinhibitory receptor encoded by programmed cell death-1 (PDCD1) gene, has a pivotal role in tolerance to self-antigens. Mutations of PDCD1 may participate in susceptibility to basal cell carcinoma (BCC) as the most common of skin cancer. We studied the impacts of two single nucleotide polymorphisms (SNPs) within PDCD1 and their haplotypes in BCC susceptibility in an Iranian...
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