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Article

Evolution of drug resistance in HIV protease.

BMC bioinformatics - 30 Dec 2020

Shah Dhara, Freas Christopher, Weber Irene T, Harrison Robert W

Abstract excerpt

BACKGROUND: Drug resistance is a critical problem limiting effective antiviral therapy for HIV/AIDS. Computational techniques for predicting drug resistance profiles from genomic data can accelerate the appropriate choice of therapy. These techniques can also be used to identify protease mutants for experimental studies of resistance and thereby assist in the development of next-generation therapies. Few studies,...

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Topics

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Share to Drug Resistance, Viral
Share to Evolution, Molecular
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to HIV Protease

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Source

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Identifiers

PMID: 33375936
DOI: 10.1186/s12859-020-03825-7
PMCID: PMC7772915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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