Article
Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study.
Journal of diabetes research - 1 Jan 2020
Zhao Mingyi, Diao Jingyi, Huang Peng, Li Jinqi, Li Yihuan, Yang Yang, Luo Liu, Zhang Senmao, Chen Letao, Wang Tingting, Zhu Ping, Qin Jiabi
Abstract excerpt
BACKGROUND: Congenital heart disease (CHD) is one of the most common birth defects among newborns, accounting for a large proportion of infant mortality worldwide. However, the mechanisms remain largely undefinable. This study aimed to investigate the association of CHD in offspring of mothers with diabetes mellitus (DM) and single nucleotide polymorphisms (SNPs) of NKX2.5. METHODS AND RESULTS: A case-control...
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