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Article

Associations of NKX2-5 Genetic Polymorphisms with the Risk of Congenital Heart Disease: A Meta-analysis.

Pediatric cardiology - 1 Jun 2016

Xie Xiaochuan, Shi Xiaohan, Xun Xiaoshuang, Rao Li

Abstract excerpt

The NKX2-5 gene is a vital regulator of cardiac formation and development. Recently, the roles of NKX2-5 63A>G polymorphism and 606G>C polymorphism in congenital heart disease (CHD) have been extensively studied, with conflicting results. The aim of the present study was to better elucidate the associations between NKX2-5 genetic polymorphisms and CHD risk through a meta-analysis. Eligible articles were searched...

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Share to Genes, Homeobox
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Defects, Congenital

Share to Homeobox Protein Nkx-2.5

Share to Polymorphism, Genetic

Share to Reproducibility of Results

Source

Identifiers

PMID: 27033241
DOI: 10.1007/s00246-016-1377-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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