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Screening NKX2.5 mutation in a sample of 230 Han Chinese children with congenital heart diseases.

Genetic testing and molecular biomarkers - 1 Apr 2009

Zhang Weimin, Li Xiaofeng, Shen Adong, Jiao Weiwei, Guan Xiaolei, Li Zhongzhi

Abstract excerpt

Congenital heart disease (CHD) is the most common developmental anomaly, affecting approximately 1% of all newborns. Genetic factors play an important role in CHD's development. Germline mutations in NK2 transcription factor related, locus 5 (NKX2.5) have been identified as the factors responsible for various forms of CHD. In this study, we investigated mutations of the NKX2.5 gene's coding region in 230...

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PMID: 19371212
DOI: 10.1089/gtmb.2008.0044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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