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Article

Novel NKX2-5 mutations responsible for congenital heart disease.

Genetics and molecular research : GMR - 29 Nov 2011

Wang J, Liu X Y, Yang Y Q

Abstract excerpt

Congenital heart disease (CHD) is the most common birth defect and is the leading cause of infant morbidity and mortality resulting from birth defects. Increasing evidence demonstrates that genetic variation in the NKX2-5 gene, which encodes a homeobox-containing transcription factor crucial to cardiogenesis, is an important molecular determinant for CHD. Nevertheless, the genetic components underlying CHD...

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Share to Genes, Dominant
Share to Heart Defects, Congenital
Share to Homeobox Protein Nkx-2.5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22179962
DOI: 10.4238/2011.November.29.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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