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Article

Associations between two genetic variants in NKX2-5 and risk of congenital heart disease in Chinese population: a meta-analysis.

PloS one - 1 Jan 2013

Wang Zhenling, Zou Li, Zhong Rong, Zhu Beibei, Chen Wei, Shen Na, Ke Juntao, Lou Jiao, Song Ranran, Miao Xiao-Ping

Abstract excerpt

BACKGROUND: NKX2-5 is a transcriptional factor, which plays an important role in heart formation and development. Two genetic variants in the coding region of NKX2-5, 63A>G (rs2277923) and 606G>C (rs3729753), have been investigated in the risk of congenital heart disease (CHD), although with inconsistent results. Thus, a meta-analysis was performed to clarify the associations between the two variants and CHD risk...

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Identifiers

PMID: 23936479
DOI: 10.1371/journal.pone.0070979
PMCID: PMC3732287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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