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Identification of Host Cellular Protein Substrates of SARS-COV-2 Main Protease

15 Dec 2020

Abstract excerpt

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease-19 (COVID-19) being associated with severe pneumonia. Like with other viruses, the interaction of SARS-CoV-2 with host cell proteins is necessary for successful replication, and cleavage of cellular targets by the viral protease also may contribute to the pathogenesis, but knowledge about the human...

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PMID: 33333742
DOI: 10.3390/ijms21249523

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