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Single cell RNA-seq identifies inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthma

2022-04-27

Abstract excerpt

Asthma is the most common chronic airways disease worldwide and the severe treatment resistant subtype of asthma is responsible for the majority of disease burden. Asthma is heterogeneous in nature and can be classified according to airway infiltrates as eosinophilic or non-eosinophilic (sometimes referred to as Type 2 low), which is further divided into paucigranulocytic (low levels of granulocytes), or neutrophi...

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Literature Corpus work
d1062eb2-5d0e-5a00-a680-68992fa7bb8a
DOI
10.1101/2022.04.26.489055
Open publication

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Single cell RNA-seq identifies inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthmaDOI 10.1101/2022.04.26.489055
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