Article

A deep lung cell atlas reveals cytokine-mediated lineage switching of a rare cell progenitor of the human airway epithelium

2023-11-29

Abstract excerpt

The human airway contains specialized rare epithelial cells whose roles in respiratory disease are not well understood. Ionocytes express the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), while chemosensory tuft cells express asthma-associated alarmins. However, surprisingly, exceedingly few mature tuft cells have been identified in human lung cell atlases despite the ready identification of rare ion...

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Literature Corpus work: 3158a4c2-09b8-5768-8f14-fc03c9fd923b
DOI: 10.1101/2023.11.28.569028

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