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Pharmacological correction of CFTR improves systemic inflammation and lung disease in Cystic Fibrosis but does not correct a basic defect in lung repair

2026-03-13

Abstract excerpt

<h4>Background</h4> Cystic Fibrosis (CF) is a lethal genetic condition affecting over 100,000 people worldwide, characterised by multi-organ dysfunction and a progressive lethal lung disease. The disease occurs due to faulty cystic fibrosis transmembrane conductance regulator (CFTR) ion channels effecting flow of chloride, bicarbonate and water out of cells. This causes thick mucus with repeated bacterial infecti...

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Literature Corpus work
308c26ab-1d47-5c04-9b49-811376935d79
DOI
10.64898/2026.03.11.26348124
Open publication

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Pharmacological correction of CFTR improves systemic inflammation and lung disease in Cystic Fibrosis but does not correct a basic defect in lung repairDOI 10.64898/2026.03.11.26348124
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