Article
DReSS: a method to quantitatively describe the influence of structural perturbations on state spaces of genetic regulatory networks.
Briefings in bioinformatics - 20 Jul 2021
Yin Ziqiao, Guo Binghui, Ma Shuangge, Sun Yifan, Mi Zhilong, Zheng Zhiming
Abstract excerpt
Structures of genetic regulatory networks are not fixed. These structural perturbations can cause changes to the reachability of systems' state spaces. As system structures are related to genotypes and state spaces are related to phenotypes, it is important to study the relationship between structures and state spaces. However, there is still no method can quantitively describe the reachability differences of two...
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