Article
Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression.
Genome research - 1 May 2011
Macneil Lesley T, Walhout Albertha J M
Abstract excerpt
In any given cell, thousands of genes are expressed and work in concert to ensure the cell's function, fitness, and survival. Each gene, in turn, must be expressed at the proper time and in the proper amounts to ensure the appropriate functional outcome. The regulation and expression of some genes are highly robust; their expression is controlled by invariable expression programs. For instance, developmental gene...
Topics
- Animals
- Gene Expression Profiling
- Gene Expression Regulation
- Gene Regulatory Networks
- Humans
- Models, Genetic
- Phenotype
- Stochastic Processes
