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Article

Investigation on changes of modularity and robustness by edge-removal mutations in signaling networks.

BMC systems biology - 21 Dec 2017

Truong Cong-Doan, Kwon Yung-Keun

Abstract excerpt

BACKGROUND: Biological networks consisting of molecular components and interactions are represented by a graph model. There have been some studies based on that model to analyze a relationship between structural characteristics and dynamical behaviors in signaling network. However, little attention has been paid to changes of modularity and robustness in mutant networks. RESULTS: In this paper, we investigated...

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PMID: 29322936
DOI: 10.1186/s12918-017-0505-2
PMCID: PMC5763305

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