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Article

Quantifying and analyzing the network basis of genetic complexity.

PLoS computational biology - 1 Jan 2012

Thompson Ethan G, Galitski Timothy

Abstract excerpt

Genotype-to-phenotype maps exhibit complexity. This genetic complexity is mentioned frequently in the literature, but a consistent and quantitative definition is lacking. Here, we derive such a definition and investigate its consequences for model genetic systems. The definition equates genetic complexity with a surplus of genotypic diversity over phenotypic diversity. Applying this definition to ensembles of...

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Identifiers

PMID: 22792055
DOI: 10.1371/journal.pcbi.1002583
PMCID: PMC3390359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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