Article
[Comparative characterization of oxidative stress in some hereditary diseases differing in predisposition of neoplasms and early aging].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 1998
Korkina L G, Trakhtman P E, Pagano D
Abstract excerpt
Two groups of hereditary diseases are considered. One group is characterized by chromosomal instability (Fanconi's anemia, ataxiatelenagioectasia, xeroderma pigmentosum). The other group includes diseases with marked genotypic changes (Down's disease, cystic fibrosis). All these diseases predispose to malignant neoplasms and premature ageing, which is due to different manifestations of oxidative stress. The paper...
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