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Article

Diagnosis of Fanconi Anaemia by ionising radiation- or mitomycin C-induced micronuclei.

DNA repair - 1 Jan 2018

Francies Flavia Zita, Wainwright Rosalind, Poole Janet, De Leeneer Kim, Coene Ilse, Wieme Greet, Poirel Hélène A, Brichard Bénédicte, Vermeulen Stephanie, Vral Anne, Slabbert Jacobus, Claes Kathleen, Baeyens Ans

Abstract excerpt

Fanconi Anaemia (FA) is an autosomal recessive disorder characterised by defects in DNA repair, associated with chromosomal instability and cellular hypersensitivity to DNA cross-linking agents such as mitomycin C (MMC). The FA repair pathway involves complex DNA repair mechanisms crucial for genomic stability. Deficiencies in DNA repair genes give rise to chromosomal radiosensitivity. FA patients have shown...

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Source

Identifiers

PMID: 29154021
DOI: 10.1016/j.dnarep.2017.11.001

Genes

FANCG
FANCA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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