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Genetic polymorphism of ESR1 rs2881766 increases breast cancer risk in Korean women.

Journal of cancer research and clinical oncology - 1 Apr 2015

Son Byung Ho, Kim Mi Kyung, Yun Young Mi, Kim Hee Jeong, Yu Jong Han, Ko Beom Seok, Kim Hanna, Ahn Sei Hyun

Abstract excerpt

PURPOSE: We performed a case-control study to evaluate the association of genetic polymorphisms of estrogen-metabolizing enzyme genes and estrogen receptor genes with breast cancer risk according to age group and subtypes in Korean women. METHODS: Breast cancer patients (n = 830) and the hospital healthy controls (n = 390) with both clinical information and SNP data were included in the study. Age was divided...

Topics

Adult
Asian People
Breast Neoplasms
Case-Control Studies
Estrogen Receptor alpha
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Multivariate Analysis

Polymorphism, Single Nucleotide

Postmenopause

Premenopause

Republic of Korea

Risk Factors

Source

Identifiers

PMID: 25323936
DOI: 10.1007/s00432-014-1849-2

Genes

ESR1
COMT
ESR2

Provenance

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