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Article

Rescue from Pseudomonas aeruginosa Airway Infection via Stem Cell Transplantation.

Molecular therapy : the journal of the American Society of Gene Therapy - 3 Mar 2021

Brinkert Kerstin, Hedtfeld Silke, Burhop Annina, Gastmeier Rena, Gad Pauline, Wedekind Dirk, Kloth Christina, Rothschuh Justin, Lachmann Nico, Hetzel Miriam, Jirmo Adan Chari, Lopez-Rodriguez Elena, Brandenberger Christina, Hansen Gesine, Schambach Axel, Ackermann Mania, Tümmler Burkhard, Munder Antje

Abstract excerpt

Cystic fibrosis is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which lead to impaired ion transport in epithelial cells. Although lung failure due to chronic infection is the major comorbidity in individuals with cystic fibrosis, the role of CFTR in non-epithelial cells has not been definitively resolved. Given the important role of host defense cells, we evaluated...

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Share to Cystic Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hematopoietic Stem Cell Transplantation

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Source

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Identifiers

PMID: 33279724
DOI: 10.1016/j.ymthe.2020.12.003
PMCID: PMC7935663

Genes

CD68
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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