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Article

Modulatory effect of rapamycin and tacrolimus on monocyte-derived dendritic cells phenotype and function.

Immunobiology - 1 Jan 2021

Dahlqvist Geraldine, Renaud Sarah, Barjon Clement, Lefebvre Anthony, Aoudjehane Lynda, Horsmans Yves, Delhem Nadira, Conti Filomena

Abstract excerpt

BACKGROUND: Immunosuppressive-drugs are needed after solid organ transplantation to prevent allograft rejection but induce severe side effects. Understanding the alloimmune response is critical to modulate it and to achieve graft operational tolerance. The role of regulatory T cells and tolerogenic dendritic cells (Tol-DCs) is undoubtedly essential in tolerance induction. Tacrolimus is considered as the...

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Identifiers

PMID: 33278711
DOI: 10.1016/j.imbio.2020.152031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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