Article
The Effect of Tacrolimus and Mycophenolic Acid on CD14+ Monocyte Activation and Function.
PloS one - 1 Jan 2017
Kannegieter Nynke M, Hesselink Dennis A, Dieterich Marjolein, Kraaijeveld Rens, Rowshani Ajda T, Leenen Pieter J M, Baan Carla C
Abstract excerpt
Monocytes and macrophages play key roles in many disease states, including cellular and humoral rejection after solid organ transplantation (SOT). To suppress alloimmunity after SOT, immunosuppressive drug therapy is necessary. However, little is known about the effects of the immunosuppressive drugs tacrolimus and mycophenolic acid (MPA) on monocyte activation and function. Here, the effect of these...
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