Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Delivery of rapamycin-loaded nanoparticle down regulates ICAM-1 expression and maintains an immunosuppressive profile in human CD34+ progenitor-derived dendritic cells.

Journal of biomedical materials research. Part A - 15 Jun 2008

Das Saswati, Haddadi Azita, Veniamin Simona, Samuel John

Abstract excerpt

Immune responses of dendritic cells (DCs) can be modulated by delivery of adjuvants to alter their maturation profile. The purpose of this study was to generate DCs from CD34(+) cells of human cord blood and characterize the effects of poly(D,L-lactic-co-glycolic acid) (PLGA)-nanoparticle encapsu...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Delivery Systems
Share to Immunosuppression Therapy
Share to Intercellular Adhesion Molecule-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lactic Acid

Share to Myeloid Cells

Share to Nanoparticles

Share to Surface Properties

Share to Toll-Like Receptor 9

Source

Identifiers

PMID: 17907241
DOI: 10.1002/jbm.a.31557

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17907241-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Delivery of rapamycin-loaded nanoparticle down regulates ICAM-1 expression and maintains an immunosuppressive profile in human CD34+ progenitor-derived dendritic cells.PMID 17907241Read ↗

Modulatory effect of rapamycin and tacrolimus on monocyte-derived dendritic cells phenotype and function.Semantic proximity Read ↗

Immunomodulatory Dual-Sized Microparticle System Conditions Human Antigen Presenting Cells Into a Tolerogenic Phenotype In Vitro and Inhibits Type 1 Diabetes-Specific Autoreactive T Cell Responses.Semantic proximity Read ↗

RAD001-mediated mTOR targeting in human monocyte-derived dendritic cells shifts them toward an immunogenic phenotype.Semantic proximity Read ↗

Immunolipoplexes: an efficient, nonviral alternative for transfection of human dendritic cells with potential for clinical vaccination.Semantic proximity Read ↗

Activation of purified allogeneic CD4(+) T cells by rat bone marrow-derived dendritic cells induces concurrent secretion of IFN-gamma, IL-4, and IL-10.Semantic proximity Read ↗

Suppression of Canine Dendritic Cell Activation/Maturation and Inflammatory Cytokine Release by Mesenchymal Stem Cells Occurs Through Multiple Distinct Biochemical Pathways.Semantic proximity Read ↗

Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking.Semantic proximity Read ↗

Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant.Semantic proximity Read ↗

Resveratrol as a natural anti-tumor necrosis factor-α molecule: implications to dendritic cells and their crosstalk with mesenchymal stromal cells.Semantic proximity Read ↗

Controlled Delivery of Immunomodulators from a Biomaterial Scaffold Niche to Induce a Tolerogenic Phenotype in Human Dendritic Cells.Semantic proximity Read ↗

Comparative study of clinical grade human tolerogenic dendritic cells.Semantic proximity Read ↗

Modification of human embryonic stem cell-derived dendritic cells with mRNA for efficient antigen presentation and enhanced potency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.