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Article

Immunosuppressive agents mediate reduced allostimulatory properties of myeloid-derived dendritic cells despite induction of divergent molecular phenotypes.

Molecular immunology - 1 Aug 2005

Duperrier Karine, Velten Florian W, Bohlender Johannes, Demory Alexandra, Metharom Pat, Goerdt Sergij

Abstract excerpt

Immunosuppressive drugs such as glucocorticoids (dexamethasone (Dexa)), cyclosporin A (CsA) and tacrolimus (Tacro) have been shown to impair differentiation and/or function of immunostimulatory dendritic cells (DC(ims)). Phenotypes and functions of the resultant myeloid dendritic cells, however, have not yet been thoroughly elucidated. We show here that all DC subsets generated by treatment with immunosuppressive...

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Identifiers

PMID: 15950746
DOI: 10.1016/j.molimm.2005.01.006

Genes

ICOS
TLR2
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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