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Article

Lipid metabolic pathways converge in motor neuron degenerative diseases

13 Nov 2019

Abstract excerpt

Motor neuron diseases (MNDs) encompass an extensive and heterogeneous group of upper and/or lower motor neuron degenerative disorders, in which the particular clinical outcomes stem from the specific neuronal component involved in each condition. While mutations in a large number of molecules associated with lipid metabolism are known to be implicated in MNDs, there remains a lack of clarity regarding the key...

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PMID: 31848577
DOI: 10.1093/brain/awz382

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