Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sphingolipid Metabolism: A New Therapeutic Opportunity for Brain Degenerative Disorders

17 Apr 2018

Abstract excerpt

Neurodegenerative diseases represent a class of fatal brain disorders for which the number of effective therapeutic options remains limited with only symptomatic treatment accessible. Multiple studies show that defects in sphingolipid pathways are shared among different brain disorders including neurodegenerative diseases and may contribute to their complex pathogenesis. In this mini review, we discuss the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular transport and secretion
Share to Lysosomal Storage Disorders Research
Share to Sphingolipid Metabolism and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29719499
DOI: 10.3389/fnins.2018.00249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sphingolipid Metabolism: A New Therapeutic Opportunity for Brain Degenerative DisordersPMID 29719499Read ↗

Neurodegenerative Disorders: Spotlight on SphingolipidsSemantic proximity Read ↗

Ceramide signalling in inherited and multifactorial brain metabolic diseasesSemantic proximity Read ↗

Potential therapeutic target for aging and age-related neurodegenerative diseases: the role of acid sphingomyelinaseSemantic proximity Read ↗

Sphingolipids in neurodegenerative diseasesSemantic proximity Read ↗

Mysterious sphingolipids: metabolic interrelationships at the center of pathophysiologySemantic proximity Read ↗

The Multiple Roles of Sphingomyelin in Parkinson's Disease.Semantic proximity Read ↗

Plasma sphingolipid abnormalities in neurodegenerative diseasesSemantic proximity Read ↗

Monogenic neurological disorders of sphingolipid metabolism.Semantic proximity Read ↗

Rescue of hippocampal synaptic plasticity and memory performance by Fingolimod (FTY720) in APP/PS1 model of Alzheimer’s disease is accompanied by correction in metabolism of sphingolipids, polyamines, and phospholipid saturation compositionSemantic proximity Read ↗

The role of Sphingolipids in myelination and myelin stability and their involvement in childhood and adult demyelinating disordersSemantic proximity Read ↗

Genetic defects in the sphingolipid degradation pathway and their effects on microglia in neurodegenerative disease.Semantic proximity Read ↗

Promising Targets for the Treatment of Neurodegenerative DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.