Article

Akaluc bioluminescence offers superior sensitivity to track <i>in vivo</i> dynamics of SARS-CoV-2 infection

2023-10-13

Abstract excerpt

<h4>Summary</h4> Monitoring in vivo viral dynamics can improve our understanding of pathogenicity and tissue tropism. For positive-sense, single-stranded RNA viruses, several studies have attempted to monitor viral kinetics in vivo using reporter genomes. The application of such recombinant viruses can be limited by challenges in accommodating bioluminescent reporter genes in the viral genome. Conventional lumi...

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Literature Corpus work: 9c8b9fc6-6557-5a47-88ee-ede82a3eff7b
DOI: 10.1101/2023.10.12.561993

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