Article
Association of matrix metalloproteinase-11 polymorphisms with susceptibility and clinicopathologic characteristics for oral squamous cell carcinoma.
Head & neck - 1 Oct 2015
Lin Chiao-Wen, Yang Shun-Fa, Chuang Chun-Yi, Lin Huang-Pin, Hsin Chung-Han
Abstract excerpt
BACKGROUND: The purpose of this study was to investigate the influence of genetic polymorphisms of the matrix metalloproteinase-11 (MMP-11) gene on the susceptibility of oral squamous cell carcinoma (OSCC). METHODS: Four single-nucleotide polymorphisms (SNPs) of the MMP-11 gene from 595 patients with oral cancer and 561 noncancer controls were analyzed by real-time polymerase chain reaction (PCR). RESULTS: MMP-11...
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