Article
A single nucleotide polymorphism in the matrix metalloproteinase-1 and interleukin-8 gene promoter predicts poor prognosis in tongue cancer.
Auris, nasus, larynx - 1 Sept 2008
Shimizu Yoshinori, Kondo Satoru, Shirai Akiko, Furukawa Mitsuru, Yoshizaki Tomokazu
Abstract excerpt
OBJECTIVE: Matrix metalloproteinase-1 (MMP-1) and interleukin-8 (IL-8) play an important role in cancer development and metastasis. There is a single nucleotide polymorphism (SNP) located in the promoter region of MMP-1 and IL-8 that regulates gene expression. MMP-1 -1607 2G/2G and IL-8 -251 A/A...
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