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Article

Functional polymorphisms and haplotypes in the promoter of the MMP2 gene are associated with risk of nasopharyngeal carcinoma.

Human mutation - 1 Nov 2007

Zhou Gangqiao, Zhai Yun, Cui Ying, Qiu Wei, Yang Hao, Zhang Xiumei, Dong Xiaojia, He Ying, Yao Kaitai, Zhang Hongxing, Peng Yong, Yuan Xiaoyan, Zhi Lianteng, Zhang Xiaoai, He Fuchu

Abstract excerpt

Matrix metalloproteinases (MMPs) play important roles in cancer initiation and development. Several polymorphisms in the promoters of a number of MMP genes, which can affect the respective MMP production in an allele-specific manner, have been well characterized. We examined whether these functional polymorphisms were related to the risk of nasopharyngeal carcinoma (NPC) in Chinese populations. Eight...

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Source

Identifiers

PMID: 17607721
DOI: 10.1002/humu.20570

Genes

MMP2
MMP1
MMP12
MMP13
MMP3
MMP7
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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