Genetically Encoded Red Photosensitizers with Enhanced Phototoxicity.

Abstract excerpt

Genetically encoded photosensitizers are increasingly used as optogenetic tools to control cell fate or trigger intracellular processes. A monomeric red fluorescent protein called SuperNova has been recently developed, however, it demonstrates suboptimal characteristics in most phototoxicity-based applications. Here, we applied directed evolution to this protein and identified SuperNova2, a protein with S10R...

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• Share to Escherichia coli
• Share to HEK293 Cells
• Share to HeLa Cells